
Stendra (Avanafil): Pharmacology, Efficacy, and Safety in Treating ED in American Males
Reading Time: 2 minutes Introduction to Stendra and Avanafil Stendra, generically known as avanafil, is a phosphodiesterase type 5 (PDE5) inhibitor approved by the FDA for the treatment of erectile dysfunction (ED) in men. This article delves into the pharmacology of avanafil, with a particular focus on its mechanism of action, pharmacokinetics, and clinical efficacy in the American male population. Mechanism of Action Avanafil's primary mode of action involves the selective inhibition of PDE5, an enzyme found predominantly in the smooth muscle of the corpus cavernosum. By inhibiting PDE5, avanafil enhances the effects of nitric oxide (NO), a chemical messenger that is released in...